It is not clear who will replace Hameed as the chief of the powerful spy agency.
Hameed was appointed as head of the spy agency on June 16, 2019, in a military shake-up. He had previously served in the ISI as the head of internal security.
Pakistan Prime Minister Imran Khan is empowered to appoint the chief of ISI. However, the choice is made by the PM in consultation with the army chief.
Lt Gen Hameed is considered as close to Army chief General Qamar Bajwa and was appointed as ISI head at a crucial time due to several external and internal security challenges.
As ISI chief, Lt Gen Hameez oversaw crucial changes in Afghanistan where the Taliban took control in August.
He even rushed to Afghanistan when the government formation talks between the Taliban and Haqqanis went sour, resulting in a scuffle during which Mullah Baradar got injured.
During his visit to Kabul, he told the media in a brief chat that “everything will be ok” in Afghanistan, when there were rumours about differences among Taliban ranks due to delay in the announcement of the government.
The Pakistani army, in an official statement, also announced two more senior-level postings.
Lt Gen Mohammad Amir was posted as Gujranwala corps commander, while Lt Gen Asim Munir was appointed as the Quarter Master General (QMG) of the Army, the statement said.
(With inputs from PTI)